Anti-Human BRD3 IP Recombinant Antibody (SAA0191) (HS898013)

Name: Anti-Human BRD3 IP Recombinant Antibody (SAA0191)
Brand: abinScience
SKU: HS898013
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HS898013

Reactividad de especies

Human

Aplicaciones

ELISA, IF, IP

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a

ID de clon

SAA0191

Objetivo

BRD3, RING3-like protein, Bromodomain-containing protein 3, KIAA0043, RING3L

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q15059

RRID

Anti-Human BRD3 IP Antibody (SAA0191) (abinScience Cat# HS898013, RRID:AB_3729725)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Bromodomain-containing protein 3 (BRD3) is a ~79 kDa protein. Chromatin reader that recognizes and binds acetylated histones, thereby controlling gene expression and remodeling chromatin structures. Recruits transcription factors and coactivators to target gene sites, and activates RNA polymerase II machinery for transcriptional elongation. In vitro, binds acetylated lysine residues on the N-terminus of histone H2A, H2B, H3 and H4. Involved in endoderm differentiation via its association with long non-coding RNA (lncRNA) DIGIT: BRD3 undergoes liquid-liquid phase separation upon binding to lncRNA DIGIT, promoting binding to histone H3 acetylated at 'Lys-18' (H3K18ac) to induce endoderm gene expression. Also binds non-histones acetylated proteins, such as GATA1 and GATA2: regulates transcription by promoting the binding of the transcription factor GATA1 to its targets.

1. LeRoy, G. et al. (2008) Molecular cell 30, 51-60. PMID: 18406326

2. Filippakopoulos, P. et al. (2012) Cell 149, 214-31. PMID: 22464331

3. Li, Y. et al. (2016) Molecular cell 62, 181-193. PMID: 27105114

4. Daneshvar, K. et al. (2020) Nature cell biology 22, 1211-1222. PMID: 32895492

5. Wai, DCC. et al. (2018) The Journal of biological chemistry 293, 7160-7175. PMID: 29567837

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human BRD3 IP Antibody (SAA0191)

Referencias

Datasheet

Anti-Human BRD3 IP Recombinant Antibody (SAA0191).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo