Anti-Human C3AR1 Recombinant Antibody (SAA0776), APC (HS803137)

Name: Anti-Human C3AR1 Recombinant Antibody (SAA0776), APC
Brand: abinScience
SKU: HS803137
Price: 290 USD
Availability: InStock

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Vista general

Número de catálogo	HS803137
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a
ID de clon	SAA0776
Conjugación	APC
Objetivo	AZ3B, HNFAG09, C3AR1, C3R1, C3a-R, C3a anaphylatoxin chemotactic receptor, C3AR
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC
Número de acceso	Q16581
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	C3a anaphylatoxin chemotactic receptor (C3AR1) is a ~53 kDa protein. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, stimulating chemotaxis, granule enzyme release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C3AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase. 1. Gao, J. et al. (2003) The Journal of biological chemistry 278, 37902-8. PMID: 12871936 2. Yadav, MK. et al. (2023) Cell 186, 4956-4973.e21. PMID: 37852260 3. Ames, RS. et al. (1996) The Journal of biological chemistry 271, 20231-4. PMID: 8702752
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human C3AR1 Recombinant Antibody (SAA0776), APC.pdf

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