

| Catalog No. | HS803107 |
|---|---|
| Species reactivity | Human |
| Applications | ELISA, FCM |
| Host species | Mouse |
| Isotype | IgG2a |
| Clone ID | SAA0776 |
| Clonality | Monoclonal |
| Target | AZ3B, HNFAG09, C3AR1, C3R1, C3a-R, C3a anaphylatoxin chemotactic receptor, C3AR |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q16581 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | C3a anaphylatoxin chemotactic receptor (C3AR1) is a ~53 kDa protein. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, stimulating chemotaxis, granule enzyme release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C3AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase. 1. Gao, J. et al. (2003) The Journal of biological chemistry 278, 37902-8. PMID: 12871936 2. Yadav, MK. et al. (2023) Cell 186, 4956-4973.e21. PMID: 37852260 3. Ames, RS. et al. (1996) The Journal of biological chemistry 271, 20231-4. PMID: 8702752 |
| Note | For research use only. |

SDS-PAGE for Anti-Human C3AR1 Antibody (SAA0776)




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