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Anti-Human C3AR1 Recombinant Antibody (SAA0776) (HS803107)

Anti-Human C3AR1 Recombinant Antibody (SAA0776)
Anti-Human C3AR1 Recombinant Antibody (SAA0776)
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Overview
Catalog No.HS803107
Species reactivityHuman
ApplicationsELISA, FCM
Host speciesMouse
IsotypeIgG2a
Clone IDSAA0776
Clonality Monoclonal
Target AZ3B, HNFAG09, C3AR1, C3R1, C3a-R, C3a anaphylatoxin chemotactic receptor, C3AR
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q16581
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

C3a anaphylatoxin chemotactic receptor (C3AR1) is a ~53 kDa protein. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, stimulating chemotaxis, granule enzyme release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C3AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase.

1. Gao, J. et al. (2003) The Journal of biological chemistry 278, 37902-8. PMID: 12871936
2. Yadav, MK. et al. (2023) Cell 186, 4956-4973.e21. PMID: 37852260
3. Ames, RS. et al. (1996) The Journal of biological chemistry 271, 20231-4. PMID: 8702752
Note For research use only.
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  • Anti-Human C3AR1 Recombinant Antibody (SAA0776)

    SDS-PAGE

    SDS-PAGE for Anti-Human C3AR1 Antibody (SAA0776)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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