

| Número de catálogo | HS803014 | ||||||||
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| Descripción |
Anti-Human C3AR1 Polyclonal Antibody (HS803014) is a rabbit polyclonal antibody detecting C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R; C3AR1; AZ3B; C3R1; HNFAG09 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human C3AR1 (Arg161-Arg340). | ||||||||
| Objetivo | C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R; C3AR1; AZ3B; C3R1; HNFAG09 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Pureza | >95% as determined by SDS-PAGE. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q16581 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | C3a anaphylatoxin chemotactic receptor (C3AR1) is a ~53 kDa protein. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a, stimulating chemotaxis, granule enzyme release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C3AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase. 1. Gao, J. et al. (2003) The Journal of biological chemistry 278, 37902-8. PMID: 12871936 2. Yadav, MK. et al. (2023) Cell 186, 4956-4973.e21. PMID: 37852260 3. Ames, RS. et al. (1996) The Journal of biological chemistry 271, 20231-4. PMID: 8702752 | ||||||||
| Nota | For research use only |




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