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Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456), APC (HY346137)

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Vista general
Número de catálogoHY346137
Reactividad de especiesHuman
AplicacionesELISA, FCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a
ID de clonSAA0456
ConjugaciónAPC
Objetivo TCP228, C-C motif chemokine 5, CCL5, T cell-specific protein P228, D17S136E, Small-inducible cytokine A5, SIS-delta, SCYA5, T-cell-specific protein RANTES, Eosinophil chemotactic cytokine, EoCP
Nivel de endotoxinas Please contact with the lab for this information.
Productos asociados Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC
Número de acceso P13501
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

C-C motif chemokine 5 (CCL5/RANTES) is a ~9 kDa protein. Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

1. Kameyoshi, Y. et al. (1992) The Journal of experimental medicine 176, 587-92. PMID: 1380064
2. Lim, JK. et al. (2005) Journal of leukocyte biology 78, 442-52. PMID: 15923218
3. Capoulade-Métay, C. et al. (2006) Immunogenetics 58, 533-41. PMID: 16791620
4. Cocchi, F. et al. (1995) Science (New York, N.Y.) 270, 1811-5. PMID: 8525373
5. Proost, P. et al. (1998) The Journal of biological chemistry 273, 7222-7. PMID: 9516414
6. Liu, B. et al. (2013) Diabetologia 56, 2467-76. PMID: 23979485
Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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