Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456) (HY346107)

Name: Anti-Human CCL5/RANTES Recombinant Antibody (SAA0456)
Brand: abinScience
SKU: HY346107
Price: 196 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.	HY346107
Species reactivity	Human
Applications	ELISA, FCM, WB
Host species	Mouse
Isotype	IgG2a
Clone ID	SAA0456
Clonality	Monoclonal
Target	TCP228, C-C motif chemokine 5, CCL5, T cell-specific protein P228, D17S136E, Small-inducible cytokine A5, SIS-delta, SCYA5, T-cell-specific protein RANTES, Eosinophil chemotactic cytokine, EoCP
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P13501
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	C-C motif chemokine 5 (CCL5/RANTES) is a ~9 kDa protein. Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). 1. Kameyoshi, Y. et al. (1992) The Journal of experimental medicine 176, 587-92. PMID: 1380064 2. Lim, JK. et al. (2005) Journal of leukocyte biology 78, 442-52. PMID: 15923218 3. Capoulade-Métay, C. et al. (2006) Immunogenetics 58, 533-41. PMID: 16791620 4. Cocchi, F. et al. (1995) Science (New York, N.Y.) 270, 1811-5. PMID: 8525373 5. Proost, P. et al. (1998) The Journal of biological chemistry 273, 7222-7. PMID: 9516414 6. Liu, B. et al. (2013) Diabetologia 56, 2467-76. PMID: 23979485
Note	For research use only.

Images

Western blot

Western blot analysis was performed using anti-CCL5/RANTES monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CCL5/RANTES (Catalog No: HY346012)
Lane 2: negative control
Bioactivity

Detects recombinant human CCL5/RANTES (Catalog No: HY346012) in indirect ELISA