

| Numéro de catalogue | HX155137 |
|---|---|
| Reactivité des espèces | Human |
| Applications | ELISA, FCM |
| Espèce hôte | Mouse |
| Clonalité | Monoclonal |
| Isotype | IgG2a, kappa |
| ID de clone | SAA0539 |
| Conjugaison | APC |
| Cible | C-C motif chemokine 7, MCP-3, CCL7, Monocyte chemotactic protein 3, Monocyte chemoattractant protein 3, NC28, Small-inducible cytokine A7, SCYA6, SCYA7, MCP3 |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Produits associés | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC |
| Numéro d'accès | P80098 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Contexte | C-C motif chemokine 7 (CCL7/MCP-3) is a ~11 kDa protein. Chemotactic factor that plays an important role in immune regulation. Attracts monocytes, eosinophils, basophils, and T-cells to sites of inflammation or infection. Upon binding to various chemokine receptors including CCR1, CCR2, CCR3, and CCR5, facilitates immune cell migration by guiding them to infected tissues. Interacts with CCR2 to facilitate the release of monocytes from the bone marrow into the bloodstream, maintaining monocyte homeostasis. In turn, monocytes recruited to inflamed or injured tissues can differentiate into macrophages or dendritic cells, which are essential for immune defense and tissue repair. 1. Bonini, JA. et al. (1997) DNA and cell biology 16, 1249-56. PMID: 9364936 2. Blanpain, C. et al. (1999) Blood 94, 1899-905. PMID: 10477718 3. Wei, H. et al. (2024) Cellular signalling 117, 111122. PMID: 38417634 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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