Anti-Human CD10/MME Recombinant Antibody (NL-1), PerCP (HY401147)

Name: Anti-Human CD10/MME Recombinant Antibody (NL-1), PerCP
Brand: abinScience
SKU: HY401147
Price: 236 USD
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Número de catálogo	HY401147
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	NL-1
Conjugación	PerCP
Objetivo	Atriopeptidase, Common acute lymphocytic leukemia antigen, Neutral endopeptidase, Skin fibroblast elastase, CD10, SFE, CALLA, Neprilysin, Neutral endopeptidase 24.11, MME, NEP, Enkephalinase, EPN
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PerCP
Número de acceso	P08473
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Neprilysin (CD10/MME) is a ~85 kDa protein. Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). 1. Rice, GI. et al. (2004) The Biochemical journal 383, 45-51. PMID: 15283675 2. Skidgel, RA. et al. (1984) Peptides 5, 769-76. PMID: 6208535 3. Gafford, JT. et al. (1983) Biochemistry 22, 3265-71. PMID: 6349683 4. Le Moual, H. et al. (1994) European journal of biochemistry 221, 475-80. PMID: 8168535 5. Wisner, A. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 17979-84. PMID: 17101991 6. Brandt, I. et al. (2006) Clinical chemistry 52, 82-7. PMID: 16254193
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.