Anti-Human Nectin-2/CD112 Recombinant Antibody (SAA2115) (HV456207)

Name: Anti-Human Nectin-2/CD112 Recombinant Antibody (SAA2115)
Brand: abinScience
SKU: HV456207
Price: 196 USD
Availability: InStock

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SDS

Vista general

Número de catálogo	HV456207
Reactividad de especies	Human
Aplicaciones	FCM, WB
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a
ID de clon	SAA2115
Aplicaciones probadas	WB
Objetivo	Nectin-2, Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Nectin cell adhesion molecule 2 receptor-related protein 2, CD112, NECTIN2, HVEB, PRR2, PVRL2
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q92692
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.09% Sodium azide. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. 1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705 2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005
Nota	For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human CD112/Nectin-2/PVRL2 Antibody (SAA2115)
Bioactivity

Detects recombinant human CD112/Nectin-2/PVRL2 (Catalog No: HV456011) in indirect ELISA
Western blot

Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: ATGE5545 200ng
Lane 2: 1* loading buffer

Referencias

Datasheet

Anti-Human Nectin-2/CD112 Recombinant Antibody (SAA2115).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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