Anti-Human CD112/Nectin-2/PVRL2 Recombinant Antibody (SAA0405), FITC (HV456117)

Name: Anti-Human CD112/Nectin-2/PVRL2 Recombinant Antibody (SAA0405), FITC
Brand: abinScience
SKU: HV456117
Price: 223 USD
Availability: InStock

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Overview

Catalog No.	HV456117
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0405
Conjugation	FITC
Clonality	Monoclonal
Target	Herpesvirus entry mediator B, Herpes virus entry mediator B, Nectin cell adhesion molecule 2, HVEB, PVRL2 receptor-related protein 2, CD112, PRR2, Nectin-2, HveB, NECTIN2
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), FITC
Accession	Q92692
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. 1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705 2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD112/Nectin-2/PVRL2 Recombinant Antibody (SAA0405), FITC.pdf

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Anti-Human CD112/Nectin-2/PVRL2 Recombinant Antibody (SAA0405), FITC (HV456117)

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