Anti-Human IL-3R alpha/CD123 Recombinant Antibody (SAA0045), APC (HB714137)

Name: Anti-Human IL-3R alpha/CD123 Recombinant Antibody (SAA0045), APC
Brand: abinScience
SKU: HB714137
Price: 290 USD
Availability: InStock

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概要
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参考文献
データシート
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概要

カタログ番号	HB714137
種反応性	Human
アプリケーション	FCM, WB
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	SAA0045
抱合	APC
テスト済みアプリケーション	FCM
ターゲット	IL-3R subunit alpha, IL-3 receptor subunit alpha, CD123, Interleukin-3 receptor subunit alpha, IL3R, IL-3R-alpha, IL3RA, IL-3RA
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
アクセッション番号	P26951
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Interleukin-3 receptor subunit alpha (CD123/IL-3Rα) is a ~43 kDa protein. Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program. 1. Huang, S. et al. (1999) Stem cells (Dayton, Ohio) 17, 265-72. PMID: 10527461
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

イメージ

Flow Cytometry

Flow-cytometry using APC anti-Human CD123 antibody. KG-1 cells were stained with an irrelevant antibody (Green Histogram) or an APC anti-Human CD123 antibody monoclonal antibody (Catalog # HB714137 , Red Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

参考文献

データシート