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Anti-Human IL-3R alpha/CD123 Monoclonal Antibody (1A567) (HB714025)

Anti-Human IL-3R alpha/CD123 Monoclonal Antibody (1A567)
Anti-Human IL-3R alpha/CD123 Monoclonal Antibody (1A567)
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Спецификация:
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Обзор
Каталожный номерHB714025
Описание
Anti-Human CD123/IL3RA Monoclonal Antibody (1A567) [1A567] (HB714025) is a mouse monoclonal antibody detecting CD123 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовHuman
ПримененияELISA, IHC, WB
Хозяинский видMouse
КлоональностьMonoclonal
ИзотипIgG
ID клона1A567
Иммуноген E. coli - derived recombinant human CD123/IL3RA (Thr19-Asp157).
Цель Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, CD123, IL3RA
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P26951
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Interleukin-3 receptor subunit alpha (CD123/IL3RA) is a ~43 kDa protein. Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program.

1. Huang, S. et al. (1999) Stem cells (Dayton, Ohio) 17, 265-72. PMID: 10527461
Примечание For research use only.
Изображения
  • Anti-Human IL-3R alpha/CD123 Monoclonal Antibody (1A567)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD123/IL3RA Monoclonal Antibody (1A567)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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