Anti-Human IL-5 R alpha/CD125 Recombinant Antibody (SAA0047) (HX243107)

Name: Anti-Human IL-5 R alpha/CD125 Recombinant Antibody (SAA0047)
Brand: abinScience
SKU: HX243107
Price: 191 USD
Availability: InStock

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概要

カタログ番号	HX243107
種反応性	Human
アプリケーション	FCM
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	SAA0047
ターゲット	IL-5R subunit alpha, IL-5 receptor subunit alpha, IL5RA, IL-5RA, IL-5R-alpha, Interleukin-5 receptor subunit alpha, CDw125, CD125, IL5R
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q01344
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Interleukin-5 receptor subunit alpha (CD125/IL5RA) is a ~47 kDa protein. Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway. 1. Monahan, J. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 159, 4024-34. PMID: 9378992 2. Tavernier, J. et al. (1992) Proceedings of the National Academy of Sciences of the United States of America 89, 7041-5. PMID: 1495999 3. Kusano, S. et al. (2012) Protein science : a publication of the Protein Society 21, 850-64. PMID: 22528658 4. Ogata, N. et al. (1998) Blood 91, 2264-71. PMID: 9516124
注意事項	For research use only.

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Flow Cytometry

Flow-cytometry using anti-human CD125 antibody.CD125 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD125 antibody monoclonal antibody (Catalog # HX243107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献

データシート

Anti-Human IL-5 R alpha/CD125 Recombinant Antibody (SAA0047).pdf

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Anti-Human IL-5 R alpha/CD125 Recombinant Antibody (SAA0047) (HX243107)

概要

イメージ

参考文献

データシート

SDS

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