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| カタログ番号 | HW589013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1971 | ||||
| ターゲット | 7B4 antigen, CD144, VE-cadherin, Cadherin-5, CDH5, Vascular endothelial cadherin | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P33151 | ||||
| RRID | Anti-Human CD144/CDH5/VE-cadherin Antibody (SAA1971) (abinScience Cat# HW589013, RRID:AB_3727735) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Cadherin-5 (CD144/CDH5) is a ~87 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Plays a role in coupling actin fibers to cell junctions in endothelial cells, via acting as a cell junctional complex anchor for AMOTL2 and MAGI1. 1. Brasch, J. et al. (2011) Journal of molecular biology 408, 57-73. PMID: 21269602 2. Shimoyama, Y. et al. (2000) The Biochemical journal 349, 159-67. PMID: 10861224 3. Lampugnani, MG. et al. (2010) Journal of cell science 123, 1073-80. PMID: 20332120 4. Abiko, H. et al. (2015) Journal of cell science 128, 1683-95. PMID: 25795300 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CD144/CDH5/VE-cadherin Antibody (SAA1971)
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