Anti-Human MCAM/CD146 Recombinant Antibody (SAA0060), PerCP (HW484247)

Name: Anti-Human MCAM/CD146 Recombinant Antibody (SAA0060), PerCP
Brand: abinScience
SKU: HW484247
Price: 268 USD
Availability: InStock

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概要
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データシート
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概要

カタログ番号	HW484247
種反応性	Human
アプリケーション	FCM
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	SAA0060
抱合	PerCP
ターゲット	CD146, Melanoma cell adhesion molecule, S-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, MUC18, MCAM, Melanoma-associated antigen MUC18, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), PerCP
アクセッション番号	P43121
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Cell surface glycoprotein MUC18 (CD146/MCAM) is a ~71 kDa protein. Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as a surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.