

| Numéro de catalogue | HW664137 |
|---|---|
| Reactivité des espèces | Human |
| Applications | FCM |
| Espèce hôte | Human |
| Clonalité | Monoclonal |
| Isotype | IgG1, kappa |
| ID de clone | SAA0061 |
| Conjugaison | APC |
| Applications testées | FCM |
| Cible | Hepatoma-associated antigen, BSG, HAb18G, 5F7, TCSF, OK blood group antigen, Collagenase stimulatory factor, CD147, Leukocyte activation antigen M6, Basigin, Extracellular matrix metalloproteinase inducer, EMMPRIN, Tumor cell-derived collagenase stimulatory factor |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Produits associés | Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC |
| Numéro d'accès | P35613 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Contexte | Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes. 1. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687 2. Redzic, JS. et al. (2011) Journal of molecular biology 411, 68-82. PMID: 21620857 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

Flow-cytometry using APC anti-human CD147 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD147 monoclonal antibody (Catalog: HW664137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.




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