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Anti-Human EMMPRIN/CD147 Recombinant Antibody (SAA0061), APC (HW664137)

Anti-Human EMMPRIN/CD147 Recombinant Antibody (SAA0061), APC
Anti-Human EMMPRIN/CD147 Recombinant Antibody (SAA0061), APC
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概要
カタログ番号HW664137
種反応性Human
アプリケーションFCM
宿主種Human
クローン性Monoclonal
アイソタイプIgG1, kappa
クローンIDSAA0061
抱合APC
テスト済みアプリケーション FCM
ターゲット Hepatoma-associated antigen, BSG, HAb18G, 5F7, TCSF, OK blood group antigen, Collagenase stimulatory factor, CD147, Leukocyte activation antigen M6, Basigin, Extracellular matrix metalloproteinase inducer, EMMPRIN, Tumor cell-derived collagenase stimulatory factor
エンドトキシンレベル Please contact with the lab for this information.
関連製品 Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
アクセッション番号 P35613
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes.

1. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687
2. Redzic, JS. et al. (2011) Journal of molecular biology 411, 68-82. PMID: 21620857
注意事項 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
イメージ
  • Anti-Human EMMPRIN/CD147 Recombinant Antibody (SAA0061), APC

    Flow CytoMetry

    Flow-cytometry using APC anti-human CD147 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD147 monoclonal antibody (Catalog: HW664137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

参考文献
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