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Anti-Human Integrin beta 2/CD18 Recombinant Antibody (SAA0815), APC (HY378137)

Anti-Human Integrin beta 2/CD18 Recombinant Antibody (SAA0815), APC
Anti-Human Integrin beta 2/CD18 Recombinant Antibody (SAA0815), APC
Цена(USD):
Спецификация:
  • 50T
  • 100T
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHY378137
Реактивность видовHuman
ПримененияELISA, FCM, WB
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1
ID клонаSAA0815
КонъюгацияAPC
Проверенные приложения FCM
Цель CD18, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, ITGB2, Integrin beta-2, MFI7
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >90% as determined by SDS-PAGE.
Связанные продукты Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
Номер доступа P05107
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон

Integrin beta-2 (CD18/ITGB2) is a ~84 kDa protein. Integrin ITGAL:ITGB2 is a receptor for ICAM1, ICAM2 and ICAM3. Integrin ITGAL:ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM:ITGB2 and ITGAX:ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX:ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM:ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain.

1. de Fougerolles, AR. et al. (1991) The Journal of experimental medicine 174, 253-67. PMID: 1676048
2. Kristóf, E. et al. (2013) Apoptosis : an international journal on programmed cell death 18, 1235-51. PMID: 23775590
3. Lacouture, C. et al. (2024) Nature communications 15, 407. PMID: 38195629
4. Swaim, CD. et al. (2017) Molecular cell 68, 581-590.e5. PMID: 29100055
5. Van der Vieren, M. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 163, 1984-90. PMID: 10438935
6. Van der Vieren, M. et al. (1995) Immunity 3, 683-90. PMID: 8777714
7. Grayson, MH. et al. (1998) The Journal of experimental medicine 188, 2187-91. PMID: 9841932
8. Barber, DF. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3653-9. PMID: 15356110
9. Ostermann, G. et al. (2002) Nature immunology 3, 151-8. PMID: 11812992
10. Bai, M. et al. (2017) Blood 130, 2092-2100. PMID: 28807980
Примечание For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
Изображения
  • Anti-Human Integrin beta 2/CD18 Recombinant Antibody (SAA0815), APC

    Flow CytoMetry

    Flow-cytometry using APC anti-human CD18 antibody. Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD18 monoclonal antibody (Catalog: HY378137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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