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Anti-Human CD213a2/IL13RA2 Recombinant Antibody (47#), PE (HC579127)

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Aperçu
Numéro de catalogueHC579127
Reactivité des espècesHuman
ApplicationsELISA, FCM, WB
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de clone47#
ConjugaisonPE
Cible IL13R, IL-13RA2, IL-13 receptor subunit alpha-2, IL-13R-alpha-2, Interleukin-13-binding protein, CD213a2, IL-13R subunit alpha-2, IL13RA2, Interleukin-13 receptor subunit alpha-2
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PE
Numéro d'accès Q14627
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Interleukin-13 receptor subunit alpha-2 (CD213a2/IL13RA2) is a ~44 kDa protein. Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1.

1. Rahaman, SO. et al. (2002) Cancer research 62, 1103-9. PMID: 11861389
2. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238
3. Fichtner-Feigl, S. et al. (2006) Nature medicine 12, 99-106. PMID: 16327802
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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