

| Número de catálogo | HB630337 |
|---|---|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, FCM |
| Especie huésped | Human |
| Clonalidad | Monoclonal |
| Isotipo | IgG1, kappa |
| ID de clon | SAA2212 |
| Conjugación | APC |
| Aplicaciones probadas | FCM |
| Objetivo | Signal transducer CD24, CD24, CD24A, Small cell lung carcinoma cluster 4 antigen |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Productos asociados | Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC |
| Purificación | Affinity chromatography. |
| Número de acceso | P25063 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Fondo | Signal transducer CD24 is a ~8 kDa protein. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. 1. Suzuki, T. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 5567-77. PMID: 11313396 |
| Nota | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |

Flow-cytometry using APC anti-Human CD24 antibody. SK-BR-3 cells were stained with an irrelevant antibody (Green Histogram) or an APC anti-Human CD24 antibody monoclonal antibody (Catalog # HB630337 , Red Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.




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