Anti-Human CD24 Recombinant Antibody (SAA2212), APC (HB630337)

Name: Anti-Human CD24 Recombinant Antibody (SAA2212), APC
Brand: abinScience
SKU: HB630337
Price: 290 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HB630337
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1, kappa
ID de clone	SAA2212
Conjugaison	APC
Applications testées	FCM
Cible	Signal transducer CD24, CD24, CD24A, Small cell lung carcinoma cluster 4 antigen
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
Purification	Affinity chromatography.
Numéro d'accès	P25063
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Signal transducer CD24 is a ~8 kDa protein. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. 1. Suzuki, T. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 5567-77. PMID: 11313396
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Flow Cytometry

Flow-cytometry using APC anti-Human CD24 antibody. SK-BR-3 cells were stained with an irrelevant antibody (Green Histogram) or an APC anti-Human CD24 antibody monoclonal antibody (Catalog # HB630337 , Red Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

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