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Anti-Human CD24 Recombinant Antibody (SAA2212), APC (HB630337)

Anti-Human CD24 Recombinant Antibody (SAA2212), APC
Anti-Human CD24 Recombinant Antibody (SAA2212), APC
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概要
カタログ番号HB630337
種反応性Human
アプリケーションELISA, FCM
宿主種Human
クローン性Monoclonal
アイソタイプIgG1, kappa
クローンIDSAA2212
抱合APC
テスト済みアプリケーション FCM
ターゲット Signal transducer CD24, CD24, CD24A, Small cell lung carcinoma cluster 4 antigen
エンドトキシンレベル Please contact with the lab for this information.
関連製品 Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
精製 Affinity chromatography.
アクセッション番号 P25063
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Signal transducer CD24 is a ~8 kDa protein. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.

1. Suzuki, T. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 5567-77. PMID: 11313396
注意事項 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
イメージ
  • Anti-Human CD24 Recombinant Antibody (SAA2212), APC

    Flow Cytometry

    Flow-cytometry using APC anti-Human CD24 antibody. SK-BR-3 cells were stained with an irrelevant antibody (Green Histogram) or an APC anti-Human CD24 antibody monoclonal antibody (Catalog # HB630337 , Red Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

参考文献
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