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Anti-Human CD24 Recombinant Antibody (SAA2212), PerCP (HB630347)

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Aperçu
Numéro de catalogueHB630347
Reactivité des espècesHuman
ApplicationsELISA, FCM
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneSAA2212
ConjugaisonPerCP
Cible Signal transducer CD24, CD24, CD24A, Small cell lung carcinoma cluster 4 antigen
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), PerCP
Purification Affinity chromatography.
Numéro d'accès P25063
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Signal transducer CD24 is a ~8 kDa protein. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.

1. Suzuki, T. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 5567-77. PMID: 11313396
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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C₂ (Working Conc.)
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Recommandation

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