

| Каталожный номер | HY466107 |
|---|---|
| Реактивность видов | Human |
| Применения | FCM, WB |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG1, kappa |
| ID клона | C219 |
| Цель | Phospholipid transporter ABCB1, MDR1, CD243, ATP-binding cassette sub-family B member 1, ABCB1, Multidrug resistance protein 1, P-glycoprotein 1, ATP-dependent translocase ABCB1, PGY1, P-Glycoprotein, P Glycoprotein |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P08183 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Фон | ATP-dependent translocase ABCB1 (CD243) is a ~141 kDa protein. Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. 1. Choi, KH. et al. (1988) Cell 53, 519-29. PMID: 2897240 2. Masud, SN. et al. (2022) Nature chemical biology 18, 1370-1379. PMID: 35970996 3. van Helvoort, A. et al. (1996) Cell 87, 507-17. PMID: 8898203 4. Chen, G. et al. (1997) The Journal of biological chemistry 272, 5974-82. PMID: 9038218 5. Shafik, SH. et al. (2022) PLoS biology 20, e3001616. PMID: 35507548 |
| Примечание | For research use only. |

SDS-PAGE for Anti-Human CD243/P-Glycoprotein Antibody (C219)




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