

| Numéro de catalogue | HW354137 |
|---|---|
| Reactivité des espèces | Human |
| Applications | FCM |
| Espèce hôte | Mouse |
| Clonalité | Monoclonal |
| Isotype | IgG1, kappa |
| ID de clone | SAA0079 |
| Conjugaison | APC |
| Cible | Apo-2 ligand, CD253, Tumor necrosis factor ligand superfamily member 10, TRAIL, APO2L, TNFSF10, Protein TRAIL, Apo-2L, TNF-related apoptosis-inducing ligand |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Produits associés | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC |
| Numéro d'accès | P50591 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Contexte | Tumor necrosis factor ligand superfamily member 10 (CD253/TNFSF10) is a ~32 kDa protein. Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. 1. Hymowitz, SG. et al. (1999) Molecular cell 4, 563-71. PMID: 10549288 2. Ramamurthy, V. et al. (2015) Acta crystallographica. Section F, Structural biology communications 71, 1273-81. PMID: 26457518 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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