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Anti-Human CD253/TNFSF10/TRAIL Recombinant Antibody (SAA0079) (HW354107)

Anti-Human CD253/TNFSF10/TRAIL Recombinant Antibody (SAA0079)
Anti-Human CD253/TNFSF10/TRAIL Recombinant Antibody (SAA0079)
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Overview
Catalog No.HW354107
Species reactivityHuman
ApplicationsFCM
Host speciesMouse
IsotypeIgG1, kappa
Clone IDSAA0079
Clonality Monoclonal
Target Apo-2 ligand, CD253, Tumor necrosis factor ligand superfamily member 10, TRAIL, APO2L, TNFSF10, Protein TRAIL, Apo-2L, TNF-related apoptosis-inducing ligand
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P50591
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Tumor necrosis factor ligand superfamily member 10 (CD253/TNFSF10) is a ~32 kDa protein. Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.

1. Hymowitz, SG. et al. (1999) Molecular cell 4, 563-71. PMID: 10549288
2. Ramamurthy, V. et al. (2015) Acta crystallographica. Section F, Structural biology communications 71, 1273-81. PMID: 26457518
Note For research use only.
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  • Anti-Human CD253/TNFSF10/TRAIL Recombinant Antibody (SAA0079)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD253/TNFSF10/TRAIL Antibody (SAA0079)

References
Formula
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