Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (SAA2021) (HT348013)

Name: Anti-Human TRAIL R2/TNFRSF10B Recombinant Antibody (SAA2021)
Brand: abinScience
SKU: HT348013
Price: 110 USD
Availability: InStock

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1mg

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Aperçu
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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HT348013

Reactivité des espèces

Human

Applications

ELISA, WB

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

VHH-hFc

ID de clone

SAA2021

Cible

CD262, DR5, Death receptor 5, KILLER, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAIL-R2, TRAILR2, TRICK2, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

O14763

RRID

Anti-Human CD262/TNFRSF10B/TRAIL-R2/DR5 Antibody (SAA2021) (abinScience Cat# HT348013, RRID:AB_3727933)
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Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Tumor necrosis factor receptor superfamily member 10B (CD262/TRAIL-R2) is a ~47 kDa protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.

1. Hymowitz, SG. et al. (1999) Molecular cell 4, 563-71. PMID: 10549288

Note

For research use only.

Isotype Control

Human IgG1 (LALAPG) Recombinant Isotype Control Antibody (HyHEL-10) (HP688307)
Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107)

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