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Drozitumab ELISA Kit (DT348038)

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Overview
Catalog No.DT348038
Description
Drozitumab ELISA Kit (DT348038) — Quantitative sandwich ELISA for Drozitumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
  • Sandwich Format — High specificity, reliable quantification.
  • High Sensitivity — Optimized for low-abundance target detection.
  • Ready-to-Use — Complete kit with pre-coated plates included.
Sample typePlasma, Serum
Sensitivity0.156 μg/ml
Range0.31-5 μg/mL
Accession O14763
Applications ELISA
Detection method Colorimetric
Assay type Quantitative
Recovery 80-120%
Shipping 2-8 ℃
Stability and Storage The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Specifications

Drozitumab

Alternate NamesPRO95780, anti-DR5, rhuMAb DR5, 912628-39-8
Background

Tumor necrosis factor receptor superfamily member 10B (Drozitumab) is a ~47 kDa protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.

1. Hymowitz, SG. et al. (1999) Molecular cell 4, 563-71. PMID: 10549288
Note For Research Use Only.
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References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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