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Anti-Human CD282/TLR2 Recombinant Antibody (OPN-305) (HT188107)

Anti-Human CD282/TLR2 Recombinant Antibody (OPN-305)
Anti-Human CD282/TLR2 Recombinant Antibody (OPN-305)
Цена(USD):
Спецификация:
  • 50ug
  • 100ug
Количество:
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  • Обзор

  • Изображения

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  • Даташит

  • SDS

Обзор
Каталожный номерHT188107
Реактивность видовHuman
ПримененияFCM
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG4, kappa
ID клонаOPN-305
Цель TIL4, Toll-like receptor 2, TLR2, Toll/interleukin-1 receptor-like protein 4, CD282
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа O60603
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон

Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also activate immune cells and promote apoptosis in response to the lipid moiety of lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

1. Jin, MS. et al. (2007) Cell 130, 1071-82. PMID: 17889651
2. Lancioni, CL. et al. (2011) Infection and immunity 79, 663-73. PMID: 21078852
3. Brightbill, HD. et al. (1999) Science (New York, N.Y.) 285, 732-6. PMID: 10426995
4. Aliprantis, AO. et al. (1999) Science (New York, N.Y.) 285, 736-9. PMID: 10426996
5. Bulut, Y. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 987-94. PMID: 11441107
6. Jung, SB. et al. (2006) Infection and immunity 74, 2686-96. PMID: 16622205
7. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712
8. Bulut, Y. et al. (2005) The Journal of biological chemistry 280, 20961-7. PMID: 15809303
9. Triantafilou, M. et al. (2006) The Journal of biological chemistry 281, 31002-11. PMID: 16880211
Примечание For research use only.
Изображения
  • Anti-Human CD282/TLR2 Recombinant Antibody (OPN-305)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD282/TLR2 Antibody (OPN-305)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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