Anti-Human CD282/TLR2 Recombinant Antibody (T2.1), APC (HT188237)

Name: Anti-Human CD282/TLR2 Recombinant Antibody (T2.1), APC
Brand: abinScience
SKU: HT188237
Price: 290 USD
Availability: InStock

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Каталожный номер	HT188237
Реактивность видов	Human
Применения	FCM, IF, WB
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	T2.1
Конъюгация	APC
Цель	TIL4, Toll-like receptor 2, TLR2, Toll/interleukin-1 receptor-like protein 4, CD282
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Номер доступа	O60603
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also activate immune cells and promote apoptosis in response to the lipid moiety of lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. 1. Jin, MS. et al. (2007) Cell 130, 1071-82. PMID: 17889651 2. Lancioni, CL. et al. (2011) Infection and immunity 79, 663-73. PMID: 21078852 3. Brightbill, HD. et al. (1999) Science (New York, N.Y.) 285, 732-6. PMID: 10426995 4. Aliprantis, AO. et al. (1999) Science (New York, N.Y.) 285, 736-9. PMID: 10426996 5. Bulut, Y. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 987-94. PMID: 11441107 6. Jung, SB. et al. (2006) Infection and immunity 74, 2686-96. PMID: 16622205 7. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712 8. Bulut, Y. et al. (2005) The Journal of biological chemistry 280, 20961-7. PMID: 15809303 9. Triantafilou, M. et al. (2006) The Journal of biological chemistry 281, 31002-11. PMID: 16880211
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.