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Anti-Human CD2AP Monoclonal Antibody (1A675) (HV416025)

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Anti-Human CD2AP Monoclonal Antibody (1A675)
Anti-Human CD2AP Monoclonal Antibody (1A675)
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Vista general
Número de catálogoHV416025
Descripción
Anti-Human CD2AP Monoclonal Antibody (1A675) [1A675] (HV416025) is a mouse monoclonal antibody detecting CD2AP in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG
ID de clon1A675
Inmunógeno E. coli - derived recombinant human CD2AP (Val2-Lys58).
Objetivo CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q9Y5K6
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

CD2-associated protein (CD2AP) is a ~71 kDa protein. Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus.

1. Kirsch, KH. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 6211-6. PMID: 10339567
2. Monzo, P. et al. (2005) Molecular biology of the cell 16, 2891-902. PMID: 15800069
3. Elbediwy, A. et al. (2012) The Journal of cell biology 198, 677-93. PMID: 22891260
Nota For research use only.
Imágenes
  • Anti-Human CD2AP Monoclonal Antibody (1A675)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD2AP Monoclonal Antibody (1A675)

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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