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Anti-Human N-Cadherin Recombinant Antibody (1H7) (HB862107)

Anti-Human N-Cadherin Recombinant Antibody (1H7)
Anti-Human N-Cadherin Recombinant Antibody (1H7)
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  • 100ug
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Aperçu
Numéro de catalogueHB862107
Reactivité des espècesHuman
ApplicationsELISA, FCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de clone1H7
Cible N-cadherin, CDH2, Cadherin-2, CD325, CDw325, Neural cadherin, CDHN, NCAD
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P19022
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Cadherin-2 (CD325/CDH2) is a ~99 kDa protein. Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells. Required for proper neurite branching.

Note For research use only.
Images
  • Anti-Human N-Cadherin Recombinant Antibody (1H7)

    Bioactivity

    Detects CD325/CDH2 in indirect ELISAs.

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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