Anti-Human Fc gamma RIIB/CD32b Recombinant Antibody (SAA0547) (HB103107)

Name: Anti-Human Fc gamma RIIB/CD32b Recombinant Antibody (SAA0547)
Brand: abinScience
SKU: HB103107
Price: 196 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HB103107
種反応性	Human
アプリケーション	ELISA, FCM, IHC, WB
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	SAA0547
テスト済みアプリケーション	FCM
ターゲット	IGFR2, FCG2, Fc-gamma RII-b, CDw32, FcRII-b, IgG Fc receptor II-b, CD32, Fc-gamma-RIIb, Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B, RHD97901
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P31994
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景	Low affinity immunoglobulin gamma Fc region receptor II-b (CD32b/FCGR2B) is a ~34 kDa protein. Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis.
注意事項	For research use only.

イメージ

SDS-PAGE

SDS-PAGE for Anti-Human CD32b/FCGR2B Antibody (SAA0547)
Bioactivity

SEC-HPLC detection for Anti-Human CD32b/FCGR2B Antibody (ABS0184).
Flow Cytometry

Flow-cytometry using anti-human CD32b antibody.CD32b Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD32b antibody monoclonal antibody (Catalog # HB103107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.