Anti-Human IGF-II R/IGF2R Reference Antibody (2B6, RUO) (HB103056)

Name: Anti-Human IGF-II R/IGF2R Reference Antibody (2B6, RUO)
Brand: abinScience
SKU: HB103056
Price: 370 USD
Availability: InStock

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SDS

Overview

Catalog No.	HB103056
Description	Anti-Human CD32b/FCGR2B (2B6) (HB103056) is a research-grade recombinant antibody targeting CD32. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	2B6
Expression system	Mammalian cells
Clonality	Monoclonal
Target	IGFR2, FCG2, Fc-gamma RII-b, CDw32, FcRII-b, IgG Fc receptor II-b, CD32, Fc-gamma-RIIb, Low affinity immunoglobulin gamma Fc region receptor II-b, FCGR2B
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P31994
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2B6
Background	Low affinity immunoglobulin gamma Fc region receptor II-b (CD32b/FCGR2B) is a ~34 kDa protein. Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

Detects Recombinant Human CD32b/FCGR2B Protein, C-His (Cat No.: HB103011) in indirect ELISA.
SDS-PAGE

SDS-PAGE for Anti-Human IGF-II R/IGF2R Reference Antibody (2B6, RUO)