

| Numéro de catalogue | HT061013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human CD337/NKp30 Nanobody (VHH2) [VHH2] (HT061013) is a alpaca monoclonal antibody detecting NKp30 in ELISA. Suitable for Human.
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| Reactivité des espèces | Human | ||||
| Applications | ELISA | ||||
| Espèce hôte | Alpaca | ||||
| Clonalité | Monoclonal | ||||
| Isotype | VHH-8His-Cys-tag | ||||
| ID de clone | VHH2 | ||||
| Cible | NKp30, LY117, NCR3, 1C7, NK-p30, CD337, Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | O14931 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Natural cytotoxicity triggering receptor 3 (CD337/NCR3) is a ~21 kDa protein. Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human CD337/NKp30 Nanobody (VHH2)




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