Anti-Human NKp30/NCR3 Reference Antibody (BGA-1833, RUO) (HT061016)

Name: Anti-Human NKp30/NCR3 Reference Antibody (BGA-1833, RUO)
Brand: abinScience
SKU: HT061016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HT061016
Description	Anti-Human CD337/NCR3 Antibody (BGA-1833) (HT061016) is a research-grade recombinant antibody targeting CD337. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1
Clone ID	BGA-1833
Expression system	Mammalian cells
Clonality	Monoclonal
Target	NKp30, LY117, NCR3, 1C7, NK-p30, CD337, Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O14931
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Natural cytotoxicity triggering receptor 3 (CD337/NCR3) is a ~21 kDa protein. Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human CD337/NCR3 Antibody (BGA-1833)

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Anti-Human NKp30/NCR3 Reference Antibody (BGA-1833, RUO).pdf

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Anti-Human NKp30/NCR3 Reference Antibody (BGA-1833, RUO) (HT061016)

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