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Anti-Human CD337/NCR3 Recombinant Antibody (BGA1831), APC (HT061137)

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Overview

Catalog No.	HT061137
Description	Anti-Human CD337/NCR3 Antibody (BGA1831), APC [BGA1831] (HT061137) is a mouse monoclonal antibody detecting CD337 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	BGA1831
Conjugation	APC
Clonality	Monoclonal
Target	NKp30, LY117, NCR3, 1C7, NK-p30, CD337, Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein
Endotoxin level	Please contact with the lab for this information.
Accession	O14931
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Natural cytotoxicity triggering receptor 3 (CD337/NCR3) is a ~21 kDa protein. Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human CD337/NCR3 Recombinant Antibody (BGA1831), APC.pdf

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Anti-Human CD337/NCR3 Recombinant Antibody (BGA1831), APC