Anti-Human CD338/ABCG2 Recombinant Antibody (5D3), PE (HV314127)

Name: Anti-Human CD338/ABCG2 Recombinant Antibody (5D3), PE
Brand: abinScience
SKU: HV314127
Price: 290 USD
Availability: InStock

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Каталожный номер	HV314127
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	5D3
Конъюгация	PE
Цель	Urate exporter, ABCP, BCRP1, ABCG2, CD338, BCRP, MXR, Broad substrate specificity ATP-binding cassette transporter ABCG2, Placenta-specific ATP-binding cassette transporter, Breast cancer resistance protein, Mitoxantrone resistance-associated protein, CDw338, ATP-binding cassette sub-family G member 2
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PE
Номер доступа	Q9UNQ0
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Broad substrate specificity ATP-binding cassette transporter ABCG2 (CD338) is a ~72 kDa protein. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary toxins and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells. Acts as a urate exporter functioning in both renal and extrarenal urate excretion. In kidney, it also functions as a physiological exporter of the uremic toxin indoxyl sulfate. 1. Komatani, H. et al. (2001) Cancer research 61, 2827-32. PMID: 11306452 2. Zhang, W. et al. (2003) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17, 2085-7. PMID: 12958161 3. Woodward, OM. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 10338-42. PMID: 19506252 4. Desuzinges-Mandon, E. et al. (2010) The Journal of biological chemistry 285, 33123-33133. PMID: 20705604 5. Taylor, NMI. et al. (2017) Nature 546, 504-509. PMID: 28554189 6. Manolaridis, I. et al. (2018) Nature 563, 426-430. PMID: 30405239 7. Toyoda, Y. et al. (2019) Cells 8. PMID: 31003562 8. Kobuchi, H. et al. (2012) PloS one 7, e50082. PMID: 23189181 9. Takabe, K. et al. (2010) The Journal of biological chemistry 285, 10477-86. PMID: 20110355
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD338/ABCG2 Recombinant Antibody (5D3), PE.pdf

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