

| Número de catálogo | HV585107 |
|---|---|
| Reactividad de especies | Human |
| Aplicaciones | FCM |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG1, kappa |
| ID de clon | NT-7 |
| Objetivo | CD352, NTB-A, NK-T-B-antigen, KALI, SLAMF6, Activating NK receptor, SLAM family member 6 |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | Q96DU3 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 0.09% Sodium azide. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Fondo | SLAM family member 6 (CD352/SLAMF6) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. Positive signaling in NK cells implicates phosphorylation of VAV1. 1. Bottino, C. et al. (2001) The Journal of experimental medicine 194, 235-46. PMID: 11489943 2. Eissmann, P. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 3170-7. PMID: 16920955 3. Chatterjee, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 1206-12. PMID: 22184727 4. Chatterjee, M. et al. (2012) The Journal of biological chemistry 287, 38168-77. PMID: 22989874 |
| Nota | For research use only. |

SDS-PAGE for Anti-Human CD352/SLAMF6 Antibody (NT-7)




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