Anti-Human NTB-A/SLAMF6 Reference Antibody (SGN-CD352A, RUO) (HV585016)

Name: Anti-Human NTB-A/SLAMF6 Reference Antibody (SGN-CD352A, RUO)
Brand: abinScience
SKU: HV585016
Price: 326 USD
Availability: InStock

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Overview

Catalog No.	HV585016
Description	Anti-Human CD352/SLAMF6 (SGN-CD352A) (HV585016) is a research-grade recombinant antibody targeting CD352. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	SGN-CD352A
Expression system	Mammalian cells
Clonality	Monoclonal
Target	CD352, NTB-A, NK-T-B-antigen, KALI, SLAMF6, Activating NK receptor, SLAM family member 6
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q96DU3
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	SGN-CD352A, SGNCD352A, SGNCD352A
Background	SLAM family member 6 (CD352/SLAMF6) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. Positive signaling in NK cells implicates phosphorylation of VAV1. 1. Bottino, C. et al. (2001) The Journal of experimental medicine 194, 235-46. PMID: 11489943 2. Eissmann, P. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 3170-7. PMID: 16920955 3. Chatterjee, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 1206-12. PMID: 22184727 4. Chatterjee, M. et al. (2012) The Journal of biological chemistry 287, 38168-77. PMID: 22989874
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human CD352/SLAMF6 (SGN-CD352A)

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Datasheet

Anti-Human NTB-A/SLAMF6 Reference Antibody (SGN-CD352A, RUO).pdf

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Anti-Human NTB-A/SLAMF6 Reference Antibody (SGN-CD352A, RUO) (HV585016)

Overview

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References

Datasheet

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