Anti-Human αIIbβ3 Recombinant Antibody (PAC-1) (HY355407)

Name: Anti-Human αIIbβ3 Recombinant Antibody (PAC-1)
Brand: abinScience
SKU: HY355407
Price: 191 USD
Availability: InStock

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Número de catálogo	HY355407
Reactividad de especies	Human
Aplicaciones	IP, WB, Block, FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgM, kappa
ID de clon	PAC-1
Aplicaciones probadas	FCM
Objetivo	CD41, ITGAB, GPIIb, ITGA2B, Platelet membrane glycoprotein IIb, GP2B, Integrin alpha-IIb, GPalpha IIb, GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A, PAC-1
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Número de acceso	P08514 & P05106
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Referencias	1. Wang F, et al. A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts. Mol Oncol. 2014 Dec;8(8):1640-52. [HY355407] 2. Seervi M, et al. ERO1α-dependent endoplasmic reticulum-mitochondrial calcium flux contributes to ER stress and mitochondrial permeabilization by procaspase-activating compound-1 (PAC-1). Cell Death Dis. 2013 Dec 19;4:e968. [HY355407] 3. Putt KS, et al. Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol. 2006 Oct;2(10):543-50. [HY355407]
Nota	For research use only.

Imágenes

Flow Cytometry

Flow-cytometry using anti-human PAC-1 antibody.Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human PAC-1 antibody monoclonal antibody (Catalog # HY355407 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry

Flow-cytometry using anti-human PAC-1 antibody.HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human PAC-1 antibody monoclonal antibody (Catalog # HY355407 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.