



| Каталожный номер | HY355407 |
|---|---|
| Реактивность видов | Human |
| Применения | IP, WB, Block, FCM |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgM, kappa |
| ID клона | PAC-1 |
| Проверенные приложения | FCM |
| Цель | CD41, ITGAB, GPIIb, ITGA2B, Platelet membrane glycoprotein IIb, GP2B, Integrin alpha-IIb, GPalpha IIb, GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A, PAC-1 |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >95% as determined by SDS-PAGE. |
| Номер доступа | P08514 & P05106 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Ссылки | 1. Wang F, et al. A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts. Mol Oncol. 2014 Dec;8(8):1640-52. [HY355407] 2. Seervi M, et al. ERO1α-dependent endoplasmic reticulum-mitochondrial calcium flux contributes to ER stress and mitochondrial permeabilization by procaspase-activating compound-1 (PAC-1). Cell Death Dis. 2013 Dec 19;4:e968. [HY355407] 3. Putt KS, et al. Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol. 2006 Oct;2(10):543-50. [HY355407] |
| Примечание | For research use only. |

Flow-cytometry using anti-human PAC-1 antibody.Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human PAC-1 antibody monoclonal antibody (Catalog # HY355407 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

Flow-cytometry using anti-human PAC-1 antibody.HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human PAC-1 antibody monoclonal antibody (Catalog # HY355407 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.




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