Anti-Human Integrin alpha 4/CD49d Recombinant Antibody (SAA0019) (HY596107)

Name: Anti-Human Integrin alpha 4/CD49d Recombinant Antibody (SAA0019)
Brand: abinScience
SKU: HY596107
Price: 196 USD
Availability: InStock

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Vista general

Número de catálogo	HY596107
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Rabbit
Clonalidad	Monoclonal
Isotipo	IgG, kappa
ID de clon	SAA0019
Aplicaciones probadas	FCM
Objetivo	ITGA4, CD49d, CD49 antigen-like family member D, CD49D, VLA-4 subunit alpha, Integrin alpha-IV, Integrin alpha-4
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P13612
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Integrin alpha-4 (CD49d/ITGA4) is a ~114 kDa protein. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. 1. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 2. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536 3. Fujita, M. et al. (2015) The Journal of biological chemistry 290, 259-71. PMID: 25398877 4. Morris, GE. et al. (2022) British journal of pharmacology 179, 4958-4973. PMID: 35802072
Nota	For research use only.

Imágenes

Flow Cytometry

Flow-cytometry using anti-human CD49d antibody. Human Jurkat cell line were stained with an irrelevant antibody (Green Histogram) or an anti-human CD49d antibody monoclonal antibody (Catalog # HY596107 , Red Histogram) at a concentration of 20 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-rabbit antibody (Catalog # PTB96441) and cells analysed on a NovoCyte Flow Cytometer.

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Datasheet