Anti-Human Integrin alpha 4/CD49d Recombinant Antibody (SAA0019) (HY596107)

Name: Anti-Human Integrin alpha 4/CD49d Recombinant Antibody (SAA0019)
Brand: abinScience
SKU: HY596107
Price: 196 USD
Availability: InStock

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Numéro de catalogue	HY596107
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Rabbit
Clonalité	Monoclonal
Isotype	IgG, kappa
ID de clone	SAA0019
Applications testées	FCM
Cible	ITGA4, CD49d, CD49 antigen-like family member D, CD49D, VLA-4 subunit alpha, Integrin alpha-IV, Integrin alpha-4
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P13612
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Integrin alpha-4 (CD49d/ITGA4) is a ~114 kDa protein. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. 1. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 2. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536 3. Fujita, M. et al. (2015) The Journal of biological chemistry 290, 259-71. PMID: 25398877 4. Morris, GE. et al. (2022) British journal of pharmacology 179, 4958-4973. PMID: 35802072
Note	For research use only.

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Flow Cytometry

Flow-cytometry using anti-human CD49d antibody. Human Jurkat cell line were stained with an irrelevant antibody (Green Histogram) or an anti-human CD49d antibody monoclonal antibody (Catalog # HY596107 , Red Histogram) at a concentration of 20 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-rabbit antibody (Catalog # PTB96441) and cells analysed on a NovoCyte Flow Cytometer.

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