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Anti-Human CD6 Recombinant Antibody (T1h) (HB797107)

Anti-Human CD6 Recombinant Antibody (T1h)
Anti-Human CD6 Recombinant Antibody (T1h)
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Aperçu
Numéro de catalogueHB797107
Reactivité des espècesHuman
ApplicationsFCM
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneT1h
Cible TP120, CD6, T12, T-cell differentiation antigen CD6
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P30203
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

T-cell differentiation antigen CD6 is a ~71 kDa protein. Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex. Functions as a costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as a calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria.

1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703
2. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938
3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806
4. Hassan, NJ. et al. (2006) Molecular and cellular biology 26, 6727-38. PMID: 16914752
5. Roncagalli, R. et al. (2014) Nature immunology 15, 384-392. PMID: 24584089
6. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728
Note For research use only.
Images
  • Anti-Human CD6 Recombinant Antibody (T1h)

    Bioactivity

    SEC-HPLC detection for Anti-Human CD6 Antibody (T1h).

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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