Anti-Human CD72 Recombinant Antibody (W004), APC (HB198137)

Name: Anti-Human CD72 Recombinant Antibody (W004), APC
Brand: abinScience
SKU: HB198137
Price: 214 USD
Availability: InStock

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Numéro de catalogue	HB198137
Reactivité des espèces	Human
Applications	FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG1
ID de clone	W004
Conjugaison	APC
Cible	CD72, Lyb-2, B-cell differentiation antigen CD72
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
Numéro d'accès	P21854
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	B-cell differentiation antigen CD72 is a ~40 kDa protein. Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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