Anti-Human CD72 Recombinant Antibody (W004) (HB198107)

Name: Anti-Human CD72 Recombinant Antibody (W004)
Brand: abinScience
SKU: HB198107
Price: 163 USD
Availability: InStock

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Overview

Catalog No.	HB198107
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1
Clone ID	W004
Clonality	Monoclonal
Target	CD72, Lyb-2, B-cell differentiation antigen CD72
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P21854
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	B-cell differentiation antigen CD72 is a ~40 kDa protein. Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis.
Note	For research use only.

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Formula

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Overview