Anti-Human CD72 Recombinant Antibody (W004), APC (HB198137)

Name: Anti-Human CD72 Recombinant Antibody (W004), APC
Brand: abinScience
SKU: HB198137
Price: 214 USD
Availability: InStock

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Overview

Catalog No.	HB198137
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1
Clone ID	W004
Conjugation	APC
Clonality	Monoclonal
Target	CD72, Lyb-2, B-cell differentiation antigen CD72
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
Accession	P21854
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	B-cell differentiation antigen CD72 is a ~40 kDa protein. Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Overview