Anti-Human CD72 Recombinant Antibody (W004), APC (HB198137)

Name: Anti-Human CD72 Recombinant Antibody (W004), APC
Brand: abinScience
SKU: HB198137
Price: 214 USD
Availability: InStock

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概要

カタログ番号	HB198137
種反応性	Human
アプリケーション	FCM
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG1
クローンID	W004
抱合	APC
ターゲット	CD72, Lyb-2, B-cell differentiation antigen CD72
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
アクセッション番号	P21854
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	B-cell differentiation antigen CD72 is a ~40 kDa protein. Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis.
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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概要