Anti-Human CD9 Recombinant Antibody (SAA0003), APC (HB984137)

Name: Anti-Human CD9 Recombinant Antibody (SAA0003), APC
Brand: abinScience
SKU: HB984137
Price: 290 USD
Availability: InStock

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概要
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データシート
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概要

カタログ番号	HB984137
種反応性	Human
アプリケーション	ELISA, FCM, WB
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1
クローンID	SAA0003
抱合	APC
ターゲット	Motility-related protein, Leukocyte antigen MIC3, TSPAN29, Cell growth-inhibiting gene 2 protein, CD9, MIC3, p24, Tspan-29, MRP-1, 5H9 antigen, Tetraspanin-29, CD9 antigen, RHD48801
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
アクセッション番号	P21926
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	CD9 antigen is a ~25 kDa protein. Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion. In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration. In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles. Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption. 1. Higginbottom, A. et al. (2003) Biochemical and biophysical research communications 311, 208-14. PMID: 14575715 2. Nakazawa, Y. et al. (2008) Blood 112, 1730-9. PMID: 18541721 3. Ikeyama, S. et al. (1993) The Journal of experimental medicine 177, 1231-7. PMID: 8478605 4. Takeda, Y. et al. (2003) The Journal of cell biology 161, 945-56. PMID: 12796480 5. Masellis-Smith, A. et al. (1994) Journal of immunology (Baltimore, Md. : 1950) 152, 2768-77. PMID: 7511626
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.